A case of spastic quadriparesis secondary to enteric fever.

Enteric fever is a systemic disease characterised predominantly by fever and abdominal pain, caused by dissemination of Salmonella Typhi or Salmonella Paratyphi. Enteric fever can affect many organ systems including liver, gastrointestinal tract, kidney and brain. Neurological manifestations occur in 2%-40% of patients and include meningitis, Gullian-Barré syndrome, neuritis and neuro-psychiatric symptoms. Spastic quadriparesis is a rare complication.

Role of Therapeutic Plasma Exchange in Resolution of Hyperhemolysis in a Patient Living with HIV/AIDS (PLHA) Diagnosed with Paroxysmal Cold Haemoglobinuria: A Case Report".

Paroxysmal cold haemoglobinuria (PCH) is an acquired cause of haemolytic anaemia. It is caused by the biphasic IgG antibodies that sensitize and attach the red cells at lower temperature; detach and rebind on rewarming. Donath-Landsteiner antibody test is the diagnostic test for PCH. Management of PCH mainly includes supportive care but sometimes disease becomes severe and life-threatening. We describe a similar severe and life-threatening case of PCH who was managed by plasma exchange followed by packed red cell transfusion.